The pre-marital screening program, funded by KACST, aims at providing accurate and low cost test for individuals or prospective couples to determine the risk of having a child with a genetic disorder. The test is based on a custom SNP-array designed to harbor the extra Saudi-specific variations.Read More
The Ministry of Health will provide a number of collection centers across the Kingdom of Saudi Arabia. The centers will collect the samples and the processing will take place in the central screening lab of King Abdulaziz City for Science and Technology (KACST).
The vision is to be a world-leader in running large scale per-marital screening program for inherited disorders. The mission is to significantly reduce the number of cases affected by inherited disorders, using up to date technologies and efficient genetic counsling.
A custom SNP-array has been designed to screen for disease variants in Saudi individuals. The SNP array is based on Affymetrix technology. It includes well known inherited disease mutations in addition to Saudi specific ones.Read More
A modern high performance computational infrastructure has been established in KACST to serve the program needs. The related software controls sample management, data analysis, and dissemination of results.
Setup of a lab capable of processing 300 thousand samples a year
Validation including robot-based automation accomplished for more than 10,000 samples
We provide tests for individuals and for couples. Individual Tests are for one individual to identify carrier status for each genomic variants. Tests for couple goes one step further and compute the risk of having children affected with inherited disorders.Read More
Clinicians can refer their patients to one of the collection centers. For other use of the screening array for diagnostic purposes, please contact the program team. The results can be forwarded to the clinician in both cases after proper registration.Read More
The Saudi population has high rate of consanguineous marriages, which lead to high rate of having children affected with inherited disorders. It is important that young couples have information about the genetic risks and do proper family planning to avoid such health problems.Read More
Individuals or couples can order the test by admitting to one of the collection centers related to the Ministry of Health. Individuals can select the type of test and subscribe to the portal for reception of the results and additional information.Read More